3 edition of Protein biosynthesis in bacterial systems. found in the catalog.
Includes bibliographical references.
|Statement||Edited by Jerold A. Last and Allen I. Laskin.|
|Series||Methods in molecular biology ;, v. 1|
|Contributions||Laskin, Allen I., 1928- joint author.|
|LC Classifications||QR84 .L35|
|The Physical Object|
|Pagination||xi, 333 p.|
|Number of Pages||333|
|LC Control Number||78160517|
Inhibitors of Protein Biosynthesis. The cytoplasmic ribosomes found in animal cells (80S) are structurally distinct from those found in bacterial cells (70S), making protein biosynthesis a good selective target for antibacterial drugs. Several types of protein biosynthesis inhibitors are discussed in this section and are summarized in Figure Holger Barth, Bradley G. Stiles, in Comprehensive Natural Products II, Bacterial protein toxins, the most toxic substances known today, are of general interest for scientists from diverse research fields because of three main reasons. From the medical perspective, certain bacterial toxins are intimately linked to a variety of severe human and animal diseases.
Bacterial Physiology and Metabolism focuses on research on bacteria, as well as metabolism of carbohydrates, fermentation, and oxidation of acids. The book first offers information on nutrition and growth of bacterial cultures, including requirements for growth, nutritional classification of bacteria, measurement of bacterial growth, and. N. meningitidis has a general system for protein O-glycosylation, which modifies PilE (Pilin), the major adhesin of N. meningitidis, and AniA, a surface exposed nitrite reductase. A model has been developed for protein O-glycosylation in this system, which is similar to wzy-dependent O-antigen biosynthesis in Gram-negative bacteria. In this.
Over the past decade, knowledge of the biosynthesis of bacterial polymers together with systems biology and synthetic biology has revolutionized . From the initial, epoch-making work of Bruce Merrifield and solid-phase peptide synthesis, the era of protein biosynthesis, along with drug-delivery and processes, has come a long way. Having mastered methods to introduce unnatural amino acids, and moieties of interest into protein chains, we are now firmly in the era of biologicals.
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Protein biosynthesis in bacterial systems (Methods in molecular biology) Hardcover – January 1, by Jerold A Last (Author) › Visit Amazon's Jerold A Last Page.
Find all the books, read about the author, and more. See search results for this author. Are you an author. Author: Jerold A Last. Additional Physical Format: Online version: Last, Jerold A. Protein biosynthesis in bacterial systems.
New York: M. Dekker, (OCoLC) protein biosynthesis by a cell-free bacterial system * Mirko Beljanski † and Severo Ochoa DEPARTMENT OF BIOCHEMISTRY, NEW YORK UNIVERSITY COLLEGE OF MEDICINE, NEW YORK, NEW YORKCited by: In contrast, the ribosome in eukaryotes is composed of a 40S and a 60S subunit, and the proteins that initiate and carry out translation of messenger RNA (mRNA) in eukaryotic systems are more complex and function differently than the proteins of bacterial systems.
The basic steps in bacterial protein synthesis are illustrated in Figure Protein biosynthesis at the ribosome results in the conversion of nucleic acid genetic information into the polypeptides essential for cellular function. Peptide bond formation requires numerous protein and nucleotide cofactors in addition to the ribosome itself, and is.
PROTEIN BIOSYNTHESIS BY A CELL-FREE BACTERIAL SYSTEM. Coronavirus: Find the latest articles and preprints PROTEIN BIOSYNTHESIS BY A CELL-FREE BACTERIAL SYSTEM.
Beljanski M 1, Ochoa S. Author information. Affiliations. 1 author. DEPARTMENT OF BIOCHEMISTRY, NEW YORK UNIVERSITY COLLEGE OF MEDICINE, NEW YORK, NEW YORK. PROTEIN BIOSYNTHESIS BY A CELL-FREE BACTERIAL SYSTEM. (PMID PMCID:PMC) Full Text Citations; Related Articles PROTEIN BIOSYNTHESIS BY A CELL-FREE BACTERIAL SYSTEM * GALE EF, FOLKES JP.
The assimilation of amino acids by bacteria. The incorporation of labelled amino acids by disrupted staphylococcal cells. This book discusses as well the result of the experiments for bacteria, which shows that DNA replication can proceed only after both template strands of the replicating molecule attach to the cell.
The final chapter deals with protein biosynthesis system in mitochondria. This book is a valuable resource for biologists and biochemists. Authoritative and cutting-edge, Bacterial Protein Secretion Systems: Methods and Protocol aims to provide techniques that are not restricted to the study of secretion systems but are also of specific interest for any researcher interested on multi-protein complexes of the bacterial cell envelope.
Here, we show that Ralstonia solanacearum, the causal agent of bacterial wilt disease, secretes the effector protein RipI, which interacts with plant glutamate decarboxylases (GADs) to alter plant metabolism and support bacterial growth.
GADs are activated by calmodulin and catalyze the biosynthesis of gamma-aminobutyric acid (GABA), an. Membrane-fusion protein homologues in gram-positive bacteria.
Mol Microbiol. ; – doi: /jx. Paulsen IT, Beness AM, Saier MH., Jr Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Microbiology. ; – Metabolism refers to all the biochemical reactions that occur in a cell or organism.
The study of bacterial metabolism focuses on the chemical diversity of substrate oxidations and dissimilation reactions (reactions by which substrate molecules are broken down), which normally function in bacteria to generate energy. Also within the scope of bacterial metabolism is the study of the uptake and.
Microbial physiology, biochemistry and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms. In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different.
This book provides an up-to-date overview of the architecture and biosynthesis of bacterial and archaeal cell walls, highlighting the evolution-based similarities in, but also the intriguing differences between the cell walls of Gram-negative bacteria, the Firmicutes and Actinobacteria, and the Archaea.
A comprehensive overview of the structural and molecular biology of cellular processes that occur at or near bacterial membranes.
The recent progress on the function and involvement of membranes in bacterial physiology enabling a greater understanding of the molecular details of the cell envelope, its biogenesis and function.
Topics include: cell wall growth, shape and division, outer membrane. Bacterial protein expression systems are popular because bacteria are easy to culture, grow fast and produce high yields of recombinant protein.
However, multi-domain eukaryotic proteins expressed in bacteria often are non-functional because the cells are not equipped to accomplish the required post-translational modifications or molecular folding. Microbial physiology, biochemistry, and genetics allowed the formulation of concepts that turned out to be important in the study of higher organisms.
In the first section, the principles of bacterial growth are given, as well as the description of the different layers that enclose the bacterial cytoplasm, and their role in obtaining nutrients from the outside media through different. Beljanski M, Ochoa S.
PROTEIN BIOSYNTHESIS BY A CELL-FREE BACTERIAL SYSTEM. Proc Natl Acad Sci U S A. Jun; 44 (6)– [PMC free article] HOAGLAND MB, KELLER EB, ZAMECNIK PC.
Enzymatic carboxyl activation of amino acids. Isao Fujii, in Comprehensive Natural Products Chemistry, Clustering of melanin biosynthesis genes. In bacteria, clustering of genes for antibiotic biosynthesis has been detected fairly early by genetic analysis.
Recent molecular genetic works established this feature unambiguously. 12 In fungi, several examples of clustered biosynthetic genes of secondary metabolites have. Protein synthesis is a complex, multi-step process involving many enzymes as well as conformational alignment.
However, the majority of antibiotics that block bacterial protein synthesis interfere with the processes at the 30S subunit or 50S subunit of the 70S bacterial ribosome. Nucleotide sequence, organization, and nature of the protein products of the carotenoid biosynthesis gene cluster of Rhodobacter capsulatus.
Mol Gen Genet. Apr; ()– Bartley GE, Scolnik PA. Carotenoid biosynthesis in photosynthetic bacteria. Genetic characterization of the Rhodobacter capsulatus CrtI protein.
Protein Biosynthesis: 1 *} Mechanisms and Regulation DONALD P. WEEKS I. Introduction II. Mechanisms of Protein Biosynthesis A. Basic Concepts B. tRNA and Amino Acid Activation C. Peptide Chain Initiation D. Peptide Chain Elongation E.
Peptide Chain Termination F. Protein Synthesis in Plant Systems G. Protein Synthesis in Prokaryotes H. Recognition of Initiator .Additional Physical Format: Online version: Last, Jerold A.
Protein biosynthesis in nonbacterial systems. New York, M. Dekker, (OCoLC)